منابع مشابه
Chronic cough in subjects with upper airway diseases - analysis of mechanisms and clinical applications
Cough is the commonest respiratory symptom leading to a medical consultation. Although acute cough which is usually associated with respiratory viral infection is not a problem to manage, chronic cough is frequently a diagnostic and therapeutic challenge as it does not respond to usual treatments. Specific group of chronic coughers are considered to have upper airway diseases, lately categorize...
متن کاملEndotype-driven treatment in chronic upper airway diseases
Rhinitis and rhinosinusitis are the two major clinical entities of chronic upper airway disease. Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) affect respectively up to 10 and 30% of the total population, hence being associated with an important socio-economic burden. Different phenotypes of rhinitis and CRS have been described based on symptom severity and duration, atopy status, lev...
متن کاملCapsaicin-sensitive cough receptors in lower airway are responsible for cough hypersensitivity in patients with upper airway cough syndrome
BACKGROUND Cough hypersensitivity may be related to the pathogenesis of upper airway cough syndrome (UACS). The purpose of the study was to investigate the role of capsaicin-sensitive cough receptors on the laryngopharynx and lower airway in the cough hypersensitivity of patients with UACS. MATERIAL AND METHODS 59 patients with UACS, 33 patients with rhinitis/sinusitis without cough, and 39 h...
متن کاملAirway oxidative stress in chronic cough
BACKGROUND The mechanisms of chronic cough are unclear. Many reactive oxygen species affect airway sensory C-fibres which are capable to induce cough. Several chronic lung diseases are characterised by cough and oxidative stress. In asthma, an association between the cough severity and airway oxidative stress has been demonstrated. The present study was conducted to investigate whether airway o...
متن کاملAspirin-sensitive asthma and upper airway diseases
BACKGROUND Aspirin exacerbated respiratory disease (AERD) consists of nasal polyposis, rhinosinusitis, asthma, and aspirin (ASA) sensitivity. OBJECTIVE This article details how to diagnose and treat AERD and describes the procedures associated with ASA challenge and desensitization, benefits associated with ASA desensitization, and appropriate doses for treatment. METHODS Criteria for diag...
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ژورنال
عنوان ژورنال: Respiratory Medicine
سال: 2010
ISSN: 0954-6111
DOI: 10.1016/j.rmed.2009.11.020